Kev sib piv ntawm Qib 1 ntshiab titanium, Qib 2 ntshiab titanium thiab titanium alloy cua sov raj rau fermentation kev lag luam

Peb cov ntaub ntawv tseem ceeb yog nquag siv hauv kev lag luam titanium cua sov raj: Qib 1 ntshiab titanium, Qib 2 ntshiab titanium, thiab titanium alloy (Ti-6Al-4V). Kev tsis sib xws loj hauv kev pabcuam lub neej yog pom nyob rau hauv cov organic acid, alternating acid-base CIP, thiab chloride-muaj fermentation media vim qhov txawv ntawm impurity cov ntsiab lus, txhua yam khoom, thiab corrosion kuj. Daim ntawv no muab cov lus pom zoo xaiv cov khoom siv rau fermentation ntau lawm kab los ntawm kev sib piv cov khoom raw muaj pes tsawg leeg, kev tiv thaiv corrosion, kev ua haujlwm zoo, cov yam ntxwv ua haujlwm, thiab tus nqi yuav khoom.

1. Core index standard rau tshuaj muaj pes tsawg leeg
Ntshiab Titanium Qib 1 (TA1)
Ti Ntau dua lossis sib npaug 99.35%, Fe Tsawg dua lossis sib npaug 0.08%, C Tsawg dua lossis sib npaug 0.05%, N Tsawg dua lossis sib npaug 0.02%, thiab H Tsawg dua lossis sib npaug 0.015%

Khoom noj khoom haus / tshuaj siab -purity standard khoom nrog tsawg hlau ion nag lossis daus txaus ntshai thiab ultra- tsis muaj hlau impurity.

Qib 2 Ntshiab Titanium (TA2, mainstream fermentation qauv)
Ti Ntau dua lossis sib npaug 99.2%, Fe Tsawg dua lossis sib npaug 0.15%, C Tsawg dua lossis sib npaug rau 0.08%, N Tsawg dua lossis sib npaug 0.03%, thiab H Tsawg dua lossis sib npaug 0.015%

Muaj cov ntsiab lus hlau me ntsis siab dua li TA1, tab sis nws ua tiav tag nrho cov fermentation los tiv thaiv - cov kev xav tau corrosion, ua tiav qhov sib npaug ntawm tus nqi thiab kev ua haujlwm.

Titanium Alloy Ti-6Al-4V
Ti matrix + 6% aluminium + 4% vanadium, nrog rau cov hlau impurity txwv ntawm 0.25%

Cov ntsiab lus alloy tseem txhim khu lub zog tensile ntawm ntshiab titanium, tab sis lawv kuj cuam tshuam nws cov tshuaj inertness tag.

2. Kev sib piv ntawm corrosion kuj (core Performance index rau fermentation apparatus)
Ntshiab Titanium Qib 1 TA1
Lowest ion nag lossis daus nyob rau hauv organic acid nruab nrab, tsis muaj kab mob ntawm fermentation broth, thiab zoo TiO₂ passive zaj duab xis compactness.

Muaj zog tiv thaiv nyob rau hauv - tso nyiaj pitting; slowest uniform etching rate nyob rau hauv ntev -lub sij hawm qaug zog acid/alternating acid- puag tu.

Qhov kev pheej hmoo ntawm hydrogen embrittlement yog tsawg heev thaum lub sij hawm inorganic acid pickling, raws li tus nqi ntawm hydrogen absorption yog qis tshaj. Kev txwv: Tsis tshua muaj kev ua haujlwm rau cov haujlwm fermentation dav dav vim yog tus nqi siab heev ntawm cov khoom siv yooj yim.

Qib 2 TA2 Ntshiab Titanium
Hauv cov tshuaj fluoride-dawb fermentation nruab nrab, qhov corrosion kuj yog qhov tshwj xeeb thiab piv rau TA1. Txawm li cas los xij, tus nqi corrosion tsuas yog me ntsis sai dua nyob rau hauv ntev - lub sij hawm siab - salinity tej yam kev mob.

Passive zaj duab xis tus kheej- kho muaj peev xwm ua tau raws li txhua hnub CIP acid- puag ncig thaum muaj cov pa oxygen txaus txaus.

Tsis muaj kev cuam tshuam cuam tshuam nrog aluminium / vanadium alloy ntsiab; ua tau raws li cov kws tshuaj GMP thiab cov qauv kev nyab xeeb khoom noj. Qhov zoo: Cov khoom siv feem ntau siv rau fermentation cua sov raj, vim nws cov nqi sib npaug thiab tiv thaiv - muaj peev xwm corrosion.

Titanium Alloy Ti-6Al-4V
Tsis txaus tiv thaiv rau scalding dilute alkali thiab organic acid: Cov khoom txhuas hauv cov hlau yuav maj mam yaj hauv qhov nruab nrab acidic, uas ua rau tsim cov hauv zos pitting pits ntawm lub raj phab ntsa.

Passive zaj duab xis yog raug rau crevice corrosion ntawm welds nyob rau hauv ib puag ncig chloride ion vim nws xoob thiab tsis sib xws.

Cov khoom fermentation yog paug los ntawm dissolving aluminium / vanadium hnyav hlau ions, uas ua txhaum cov zaub mov thiab tshuaj huv cov qauv. Cov xwm txheej txwv tsis pub: Tag nrho cov khoom noj, dej haus, thiab tshuaj fermentation tanks; tsuas yog tsis yog -corrosive mechanical structural element tau tso cai, thiab cov cua kub yuav tsum tsis txhob cuam tshuam nrog qhov nruab nrab.

3. Kev ua kom yoog raws thiab kev ua haujlwm zoo
Tensile zog thiab ductility
Ti-6Al-4V alloy: Pom lub zog tensile siab tshaj plaws, hardness, compression, thiab cuam tshuam tsis kam; Txawm li cas los xij, nws yog qhov nyuaj rau khoov thiab tsim, thiab nws muaj zog ductility.

TA1 / TA2 ntshiab titanium yog ib yam khoom uas zoo - haum rau txoj kev flanged cua sov tube welding vim nws zoo heev ductility, tsis tshua muaj tensile zog, thiab zoo dabtsi yog khoov thiab ua hauj lwm zoo.

Vuam efficiency
TA1 & TA2: Kev tiv thaiv corrosion tsis zoo nrog lub raj lub cev, du weld passive zaj duab xis tom qab refining, ruaj khov argon arc vuam.

Ti-6Al-4V: Lub weld cheeb tsam grain coarsens, ua rau muaj qhov tseem ceeb hauv zos corrosion nyiam tom qab vuam. Weld tshav kub-cuam tshuam cheeb tsam ua ib tug corrosion tsis muaj zog point.

Thermal cycling adaptability
Ntshiab titanium (TA1 / TA2) nthuav tawm cov thermal expansion coefficient, me me thermal stress thaum lub sij hawm cua sov heev - kaw lub voj voog, thiab ib tug passive zaj duab xis microcrack tiam ceev uas yog ho qis dua cov titanium alloy. Nyob rau hauv qhov kub thiab txias, cov raj hlau alloy muaj qhov cuam tshuam rau cov yeeb yaj kiab nrawm nrawm.

4. Kev tsis sib xws ntawm tus nqi
Tus nqi ntawm purified titanium raw khoom hauv TA1 Qib 1 yog kwv yees li 25% mus rau 35% siab dua li ntawm TA2.

TA2 Qib 2 ntshiab titanium yog cov khoom siv loj loj uas muaj nqi me ntsis.

Tus nqi raw khoom ntawm Ti-6Al-4V alloy yog piv rau TA2. Txawm li cas los xij, tag nrho cov khoom tiav tag nrho cov nqi tsis qis dua TA2, thiab nws muaj subpar anti-corrosion rov qab los ntawm kev ua haujlwm siab thiab vuam rework nqi.

5. Kev taw qhia rau kev xaiv cov ntaub ntawv qib rau fermentation tej yaam num
Scenario 1: Ib qho kev txwv hnyav hnyav, siab -tus nqi roj ntsha roj ntsha, thiab siab -tus qauv tshuaj sterile fermentation
Kev xaiv: Qib 1 TA1 ntshiab titanium cua sov raj Qhov laj thawj rau ultra- lub neej ua haujlwm ntev yog qhov tsis muaj hlau ion paug, ultra- hlau impurity tsawg, thiab nquag nqus CIP ntxuav.

Scenario 2: Kev tsim khoom tsis tu ncua rau 24 teev, cov kua qaub li niaj zaus -piv CIP, cov khoom noj khoom haus fermentation, thiab organic acid brewing.
Kev xaiv: Qib 2 TA2 ntshiab titanium cua sov raj (kev lag luam tus qauv kev pom zoo) Lub ntsiab yog vim li cas: GMP raws, corrosion kuj yog tag nrho txaus los txaus siab, thiab kev yuav khoom thiab tu cov nqi sib npaug.

Scenario 3: Concentrated alkali txheej txheem, nruab nrab nrog kab fluoride, simmering
Kev xaiv: Tshem tawm kev siv tag nrho cov ntaub ntawv titanium thiab siv lub raj cua sov uas yog coated tag nrho hauv PFA. Yog vim li cas rau qhov no yog tias ob qho tib si ntshiab titanium thiab titanium alloys yuav ntsib teeb meem loj etching tsis ua hauj lwm.

Scenario 4: General mechanical structure tsis muaj kev sib cuag nruab nrab
Txwv tsis pub: Txhua lub raj cua sov rau hauv fermentation broth, alloy caij dissolution ua rau cov khoom scrapping. Kev xaiv: Ti-6Al-4V titanium alloy.

6. Cov lus piv txwv
Tswv yim:

Kev ntsuam xyuas Dimension Qib 1 TA1 Ntshiab Titanium Qib 2 TA2 Ntshiab Titanium Ti-6Al-4V Titanium Alloy
Corrosion kuj uas yog nruab nrab, nrog tsawg tsawg fracturing riskExcellent, haum rau feem ntau ntawm fermentation txheej txheemAluminium yog ib tug tsis zoo hlau uas yaj nyob rau hauv acid los tsim pits.
Kev pheej hmoo kis kab mob cuam tshuam nrog cov khoom fermentation Yuav luag tsis muaj Tsis tshua muaj qis, txaus siab rau cov khoom noj thiab cov qauv tshuajA qib siab ntawm nag lossis daus ntawm aluminium / vanadium ions
Thermal cycling thiab weld performancePassive zaj duab xis uas yog homogeneous thiab ruaj khovMainstream vuam cov khoom uas ruaj khov Weld grain coarsening thiab ceev cov yeeb yaj kiab tawg
susceptibility rau hydrogen embrittlementLow nruab nrab siab
Tus nqi ntawm cov ntaub ntawv nyoosHighest Nruab Nrab, tus nqi-effectiveIn ze ze rau TA2, muaj tus nqi tseem ceeb cuam tshuam nrog kev tshaj tawm- ua.
Fermentation tank uas tsim nyog Pharmaceutical fermentation nyob rau theem siab tshaj ntawm sterilityTxhua cov pa tshuaj thiab zaub mov fermentationMedium-cov khoom siv cua sov yog txwv tsis pub.
Condensed Summary
Lub Ti-6Al{10}}4V titanium alloy yog mechanically robust; Txawm li cas los xij, nws tsis tsim nyog rau fermentation cua sov raj vim nws tsis txaus acid corrosion tsis kam thiab muaj kev pheej hmoo ntawm cov hlau hnyav. Qhov kev xaiv zoo tshaj plaws rau feem ntau ntawm fermentation cov kab ntau lawm yog Qib 2 TA2 ntshiab titanium, uas muaj kev sib npaug ntawm kev ua tau zoo thiab tus nqi. Qib 1 TA1 ntshiab titanium tshwj xeeb yog siv nyob rau hauv siab -purity sterile cov txheej txheem tshuaj uas yuav tsum tau nruj impurity tswj. Hauv cov xov xwm uas muaj fluoride, tsis muaj cov khoom siv titanium muaj peev xwm ua haujlwm tau zoo; Yog li ntawd, PFA-coated cua sov raj yuav tsum tau ua haujlwm.